Sajad Parvar; Ali Khaledi; Ali Riazi
Abstract
Background: Craniosynostosis, defined as the premature fusion of the cranial sutures, which can causes impair brain development and cognitive problems. Objective: The purpose of this study was to assess the epidemiological features of children with craniosynostosis. This information includes the characteristics ...
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Background: Craniosynostosis, defined as the premature fusion of the cranial sutures, which can causes impair brain development and cognitive problems. Objective: The purpose of this study was to assess the epidemiological features of children with craniosynostosis. This information includes the characteristics of the patients, their parents as well as their socioeconomic status. Methods: This is a cross-sectional study performed from 2015 to 2020 in Imam Hossein Children's Hospital, Isfahan, Iran. We included 220 patients, under craniosynostosis treatment. A multidisciplinary team examined all participants. CT-scan was performed on all patients. All of the participants underwent surgical intervention. The recorded information was classified into four sections: characteristic data of children with craniosynostosis, Family history and parental information, including underlying diseases and drug history 3. Socioeconomic status 4. Treatment and surgery.Results: 151 (68.7%) of participants were male and 171 (77.9%) had term delivery. The average birth weight was 2.92 kg and head circumference were 34.4 cm. the mean age of children at the time of surgery was 7.74 months and the mortality rate was 3 (1.4%). moreover, 90% were operated once and 10% were operated 2 or 3times. the most common type of craniosynostosis was Metopic 59 (59.4%). In relation to parenteral data, 96 (43.6%) of parents had consanguineous marriage and 6.4% had 1st and 2nd degree family with craniosynostosis. Conclusion: Based on these findings, attention must be directed towards the potential risk of craniosynostosis in offspring born to consanguineous couples. Moreover, parents must receive guidelines for managing children affected by craniosynostosis.
Ali Riazi; Ali Abbasivand; Alireza Arabi; Mehrdad Larry
Abstract
Background: Craniosynostosis refers to the premature fusion of cranial sutures. Premature closure can impair brain development and cognitive problems. Only available treatment of craniosynostosis is through surgical intervention which is associated with excessive blood loss.Objectives: In this study, ...
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Background: Craniosynostosis refers to the premature fusion of cranial sutures. Premature closure can impair brain development and cognitive problems. Only available treatment of craniosynostosis is through surgical intervention which is associated with excessive blood loss.Objectives: In this study, we investigate the prevalence of each ABO/Rh blood group amongst patients with different types of craniosynostosis.Methods: We included 163 patients, under craniosynostosis treatment, in Imam Hossein children’s hospital at Isfahan, Iran. A retrospective analysis was performed and the frequency of blood groups as well as types of craniosynostosis were reported. Moreover, the connection between ABO/Rh blood groups and the types of craniosynostosis was examined by chi-square test.Results: Of 163 cases reviewed; The majority of participants had blood group A positive (32.5%), followed by O positive (31.3%). The rest of the blood groups were reported in order: B positive (22.1%), B negative (4.9%), AB positive (4.3%), O negative (2.5%), A negative (1.8%), AB negative (0.6%). Also, the most common type of craniosynostosis was metopic (27%) and the other types were pansynostosis (23.9%), sagittal (21.5%), coronal (16.6%), multisuture (10.4%) and lambdoid (0.6%) respectively. Due to connection between ABO/Rh blood groups and the types of craniosynostosis, no significant relationship was observed.Conclusion: Based on the results of the present study, it was found that the frequency of ABO blood groups in children with craniosynostosis can be different from the population of the same area. Also, the ratio of different types of craniosynostosis was different from previous data.
Ali Riazi; Mostafa Allami; Alireza Arabi; Mehrdad Larry
Abstract
Background: Craniosynostosis is a congenital deformity of the skull that occurs at birth.Objectives: This study aimed to investigate the frequency of different types of craniosynostosis in Isfahan, Iran.Methods: In this retrospective study, the records of all patients referred to the pediatric neurosurgery ...
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Background: Craniosynostosis is a congenital deformity of the skull that occurs at birth.Objectives: This study aimed to investigate the frequency of different types of craniosynostosis in Isfahan, Iran.Methods: In this retrospective study, the records of all patients referred to the pediatric neurosurgery clinic of Imam Hossein children’s hospital in Isfahan, Iran from 2013 to 2018 were diagnosed with craniosynostosis. Incomplete files were excluded. Demographic information of patients and type of delivery, underlying diseases of their parents, diseases of maternal pregnancy, type of craniosynostosis, syndromic or non-syndromic craniosynostosis were collected. Data were analyzed using SPSS software version 22.Results: The diagnosis of craniosynostosis in 63% of cases (n=121) was a single suture and in 37% of cases (n=72) was a complex suture. There was no significant difference in the frequency distribution of craniosynostosis in males and females (P>0.05).Conclusion: Due to the prevalence of 16 cases per 100,000, we can reduce the complications of this disease by educating doctors and parents.